Publications

Selected research contributions from the Huang Lab in plant specialized metabolism and synthetic biology

Jump to: 2025 2024 2023 Earlier

2025

Research Article

A dirigent protein redirects extracellular terpenoid metabolism for defense against biotic challenges.

Lin JL, Wu WK, Nie GB, Li JX, Fang X, Sheng YG, Wang MM, Zheng QY, Guo XX, Huang JF, Ma LY, Wang LJ, Liu JX, Wang SS, Xu B, Gao Y, Li Y, Wang D, Martin C, Chen XY*, Huang JQ*.

Nature Communications. 2025, 16: 9270

DOI Link
Research Article

SPL1 positively regulates cuticular ridge wax biosynthesis in Arabidopsis

Hui-Xian Zhu, Jia-Fa Huang, Jun-Feng Cao, Ling-Jian Wang, Huang JQ*.

Plant Stress. 2025, 16: 100872

DOI Link
Research Article

Cotton metabolism regulatory network: Unraveling key genes and pathways in fiber development and growth regulation.

Yang ZR, ..., Huang JQ, et al.

Plant Communications. 2024, 101221.

DOI Link
Research Article

Gamma-selinene synthase catalyzes the first step of dihydroagarofuran sesquiterpene alkaloid biosynthesis in Tripterygium.

Fang X, Chen XY, Huang JQ, et al.

Science China Life Sciences. 2025, DOI: 10.1007/s11427-025-3121-9.

DOI Link

2024

Research Article

Regulation of glandular size and phytoalexin biosynthesis by a negative feedback loop in cotton.

Wu WK#, Nie GB#, Lin JL#, Huang JF#, Guo XX, Chen M, Fang X, Mao YB, Li Y, Wang LJ, Tao XY, Gao Y, Yang ZR, Huang JQ*.

Advanced Science. 2024, 11(30): e2403059

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2023

A dirigent protein complex directs lignin polymerization and assembly of the root diffusion barrier.

Gao YQ#, Huang JQ#, Reyt G, Song T, Love A, Tiemessen D, Xue PY, Wu WK, George MW, Chen XY, Chao DY*, Castrillo G*, Salt DE*.

Science. 2023, 382(6669): 464-471

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Dirigent gene editing of gossypol enantiomers for toxicity-depleted cotton seeds.

Lin JL, Fang X, Li JX, Chen ZW, Wu WK, Guo XX, Liu NJ, Huang JF, Chen FY, Wang LJ, Xu B, Martin C, Chen XY*, Huang JQ*.

Nature Plants. 2023, 9(4): 605-615

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Single-cell RNA sequencing reveals a hierarchical transcriptional regulatory network of terpenoid biosynthesis in cotton secretory glandular cells.

Lin JL#, Chen L#, Wu WK, Guo XX, Yu CH, Xu M, Nie GB, Dun JL, Li Y, Xu B, Wang LJ, Chen XY, Gao W*, Huang JQ*.

Molecular Plant. 2023, 16(12): 1990-2003

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News & Views

Removing the toxic enantiomer from crop products with selective gene editing.

Huang JQ and Chen XY.

Nature Plants. 2023, 9(4): 513-514

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2021 - 2020

Recent advances and future perspectives in cotton research.

Huang G, Huang JQ, Chen XY, Zhu YX.

Annual Review of Plant Biology. 2021, 72: 437-462

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Aromatization of natural products by a specialized detoxification enzyme.

Huang JQ#, Fang X#, Tian X, Chen P, Lin JL, Guo XX, Li JX, Fan Z, Song WM, Chen FY, Ahati R, Wang LJ, Zhao Q, Martin C, Chen XY*.

Nature Chemical Biology. 2020, 16(3): 250-256

DOI Link

RES transformation for biosynthesis and detoxification.

Huang JQ, Lin JL, Guo XX, Tian X, Tian Y, Shangguan XX, Wang LJ, Fang X, Chen XY.

Science China Life Sciences. 2020, 63(9): 1297-1302

DOI Link

Genome-wide characterization of the GRF family and their roles in response to salt stress in Gossypium.

Cao JF, Huang JQ, Liu X, Huang CC, Zheng ZS, Zhang XF, Shangguan XX, Wang LJ, Zhang YG, Wendel JF, Grover CE, Chen ZW.

BMC Genomics. 2020, 21(1): 575

DOI Link

Earlier Publications

Tian X, Huang JQ#, et al. (2018) Characterization of gossypol biosynthetic pathway. PNAS. [DOI]

Tian X, Huang JQ#, et al. (2019) A gossypol biosynthetic intermediate disturbs plant defence response. Phil. Trans. R. Soc. B. [DOI]

Fang X, Huang JQ, et al. (2017) Systematic identification of functional residues of Amorpha-4,11-diene synthase. Biochem J. [DOI]

Tian X, Huang JQ, et al. (2016) Gossypol: phytoalexin of cotton. Sci China Life Sci. [DOI]